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More scientific study is needed to determine their efficacy
The mutant TDP-43 and SOD1 proteins can form cytosolic aggregates, which affect the stability of mRNA through an interaction with mRNA species in ALS (Strong, 2010)
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Statins promote the progression of peripheral neuropathy and rhabdomyolysis, though the association of statins with upper motor lesions was disproportionate (Edwards et al., 2007)
