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Levine M, Conry-Cantilena C, Wang Y, Welch RW, Washko PW, Dhariwal KR et al (1996) Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance
10.3389/fphys.2018.01942 214

Polymers with a high molecular weight are desirable because they provide more bonding sites
You might feel a bit of pressure or a small pinch