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Clinical trials in patients with chronic insomnia showed mixed results, with some studies reporting improvements in sleep quality, reduced sleep latency, and better sleep maintenance, while others found minimal effects or inconsistent responses

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These include, amongst others: 49 Various infections / infectious diseases Renal pelvic inflammation Heart valve inflammation Tuberculosis Tumors of the immune system, gastrointestinal tract or kidneys Diseases of the connective tissue Inflammations of the blood vessels Rheumatological diseases Ulcerative colitis Crohns disease Chronic or alcohol-related hepatitis Thyroid or pancreatitis Hormonal disorders Diseases of the nervous system Allergies Thrombosis A reduction in body temperature (hypothermia), on the other hand, can be caused by circulatory collapse, hypothyroidism (underactive thyroid), or severe weight loss (cachexia), among other things