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For instance, immune cells deploy a potent radical-to-non-radical oxidant cascade (O 2 H 2 O 2 HOCl/ONOO ) for host defense, while generic cellular homeostasis relies on non-radical H 2 O 2 to fine-tune kinase/phosphatase networks governing growth and adaptation [1113]

doi: 10.1124/mol.65.3.550

This leads to effective skin lightening, reduction in pigmentation, and a brighter, more radiant complexion with consistent use
For example, GSTs inactivate the 8,9-epoxide formed by the CYP450-catalyzed oxidation of the environmental toxicant/carcinogen aflatoxin B1, Figure 3a