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In turn, the increase in intracellular zinc may have a cytoprotective effect by limiting the production of NO through the inhibition of iNOS (222)
Likewise, there is greater proliferation of human umbilical vein endothelial cells (HUVECs), significantly promoted migration of HUVECs (transwell assay), and the upregulated expression of VEGF-a, and accelerated vascular tube formation in vitro (Huang et al., 2015)