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AOD 9604 fat reduction in obese subjects Heffernan MA et al
Using a streptozotocin-induced diabetic mouse model, the researchers demonstrated that systemic administration of BHB, an endogenous HCAR2 ligand, significantly reduced retinal endoplasmic reticulum (ER) stress and NLRP3 inflammasome activation, both of which are key contributors to diabetic retinopathy
Modulation of these receptors can affect normal brain development and therefore result in autism
