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Induction of Pathogenic TH17 Cells by Inducible Salt-Sensing Kinase SGK1

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Histone acetylation Histone acetylation via histone acetyltransferases (HATs) is a critical epigenetic modification that neutralises the lysine residues of histone proteins to open the chromatin structure and regulates gene expression, which can be reversed by histone deacetylases (HDACs) to remove the acetyl groups

When Paeoniflorin combined with RIPostC to treat I/R injury, studies demonstrated that the combination therapy, compared with RIPostC or paeoniflorin alone, markedly inhibited neutrophil accumulation