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Women using oral contraceptives should be counseled about this potential interaction and may need to consider alternative or additional contraceptive methods, particularly during the initial weeks of treatment when gastric emptying effects may be most pronounced

Suspected neurological involvement due to B12 deficiency warrants urgent initiation of treatment and may require specialist referral

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Experimental data also propose that Epithalon may modulate histone-DNA interactions, potentially altering chromatin accessibility and influencing transcription processes