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Single-cell and spatial transcriptome analysis reveals the cellular heterogeneity of liver metastatic colorectal cancer

Withania somnifera inhibits NF-B and AP-1 transcription factors in human peripheral blood and synovial fluid mononuclear cells

78 However, it is worth noting that other studies showed that transgenic expression of CETP in mice increases RCT by promoting clearance of cholesterol via the hepatic LDL receptor

Genetic knockout models provided robust reverse validation: In Nrf2-KO mice, the neuroprotective effects of Tripterygium wilfordii extract nearly disappeared, indicating a strict dependence on Nrf2 activation