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The mechanism by which liver fibrosis occurs remains largely elusive

Humanized mouse models, particularly NSG-SGM3 mice engrafted with human hematopoietic stem cells, exhibit a functionally human immune system comprising myeloid and lymphoid lineages

Evidence that paraquat causes opening of the cyclosporin A-sensitive permeability transition pore synergistically with nitric oxide

CD44 is expressed on leukocytes and has a role in mediating the innate immune response