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For example, studies in mice using gut microbial metabolites that restore intestinal barrier function and reduce inflammatory cytokines also resulted in lower BP [96]
doi: 10.1186/s12934-020-01421-1
In the MPTP mouse model, MPTP is metabolized to MPP + in glial cells and accumulates in dopaminergic neurons via the dopamine transporter, causing selective neurodegeneration and oxidative stress
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