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NICE-appraised licensed alternatives such as semaglutide (Wegovy) and liraglutide (Saxenda) are available through regulated UK weight management services

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Insulin resistance, hyperinsulinemia, dyslipidaemia, and obesity precede the progression to T2D in 7585 % of patients [65], and the presence of MetS increases up to fivefold the risk for T2D compared to individuals without MetS [66, 67]

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In a home setting, patients should have a designated spot in their refrigerator to store it safely (ideally in a container to avoid contact with food items and with the original box around it)

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