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Licht-Mayer S, Wimmer I, Traffehn S et al (2015) Cell type-specific Nrf2 expression in multiple sclerosis lesions

Currently, the only ghrelin receptor-targeting drug approved in Japan is anamorelin, an agonist used to treat cancer cachexia

Candidate proteins were selected based on a paired Welchs t-test and z-score thresholds

Further, NAPQI is conjugated with glutathione to form acetaminophen-glutathione conjugate (APAP-SG) causing a significant glutathione depletion and oxidative stress leading to cell impairment or death (Jaeschke and Bajt 2006
