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Inhibiting NNMT with 5-amino-1MQ reverses this: NAD+ levels rise, mitochondrial respiration increases, and white adipose tissue (fat storage) shifts toward thermogenesis
Interdependence of cell growth and gene expression: origins and consequences
[DOI] [PMC free article] [PubMed] [Google Scholar] 147.Trovato A., Siracusa R., Di Paola R., Scuto M., Ontario M.L., Bua O., Di Mauro P., Toscano M.A., Petralia C.C.T., Maiolino L., et al
KeaneKNHinchliffePMRowlandsPKBorudeGSrinivasanSDhaliwalSSet al
