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2 The TME drives the epigenetic reprogramming of Tregs 2.1 The epigenetic features of Tregs in the TME 2.1.1 DNA methylation DNA methylation is an important epigenetic mechanism that regulates gene expression without altering the underlying DNA sequence, thereby influencing processes such as cell differentiation, development, and disease progression (Jones, 2012

doi: 10.3390/biomedicines9070744 10.3390/biomedicines9070744 Sikiric.P, Hahm.K, Blagaic.A, Tvrdeic.A, Pavlov.K, Andrea Petrovic.A, Stable Gastric Pentadecapeptide BPC 157, Roberts Stomach Cytoprotection/Adaptive Cytoprotection/Organoprotection, and Selyes Stress Coping Response: Progress, Achievements, and the Future

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