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The compound moved through Phase I trials, which primarily assess safety in humans, and appeared to have a very favorable safety profile

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Meanwhile, insufficient extracellular methionine supply in the tumor microenvironment augments PD-1 expression through decreasing the H3K79me2 level in CD4 + T cells (123)

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doi: 10.1016/j.foodres.2015.05.039 84

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Journal of Neuroscience Methods, 128, 159172

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