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Recent assessments estimate that adults may ingest on the order of 10 3 10 5 particles per day (equivalent to gmg/day depending on particle size and density) and inhale a similar magnitude annually [131,132,133]

In patients with PF, the progression of fibrosis is believed to be influenced by three primary factors: excessive epithelial damage caused by inhaled pollutants, senescence, and genetic susceptibility [32]

12, 22822289, 10.2337/dc19-0869
