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148 In addition to instigating the XBP1s-mediated transcriptional response, activated IRE1 also serves as a scaffolding protein that facilitates the activation of other signaling pathways

Shi SS, Yang WZ, Tu XK, Wang CH, Chen CM, Chen Y

The panel chair was a gastroenterologist

Because the gut is the primary site of nutrient absorption, its health dictates how well every other system in your body functions
