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Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer
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MCF-7 cells stably overexpressing IGF-1 induce significantly higher tumor volumes compared with control or mock cells in mouse xenografts [51]
Some affected metabolites link to amino acid metabolism and changes in key pathways such as amino acid metabolism has been observed (184, 187, 408, 409)
