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Alzheimers disease is currently diagnosed based on several factors, including amyloid plaques and tau tangles, neurofibrillary tangles (NFTs), which are toxic proteins in the brain tissue and result in cognitive decline and eventually dementia

[DOI] [PMC free article] [PubMed] [Google Scholar] 56.Escamilla-Cruz M., Magaa M., Escandn-Perez S., Bello-Chavolla O.Y

Fourthly, the A peptide has binding affinity for metal ions such as Zinc (Zn), copper (Cu) and iron (Fe), resulting in formation of the metal complexes Zn(II)-A, Cu(I/II)-A and Fe(II/III)-A, respectively

Affinity tags are appended to proteins so that they can be purified from their crude biological source using an affinity technique