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glutathione and alzheimer's disease Frontiers India clinical trial to evaluate
Description
Psychiatry 67, 10101016
10.3390/antiox10040508 Antioxidants 30 KawashimaC
Evidence: Well-validated across many injury types
In addition, cellular ROS accumulation inevitably causes intrinsic damage of both nuclear and mitochondrial DNA, resulting in the aberrant presence of cytosolic double-stranded DNA (dsDNA) fragments, which serve as strong agonist of cGAS-STING-dependent innate immune signaling pathway [36, 37]
