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Le concentrazioni plasmatiche di GHK-Cu sono pi alte in giovent (circa 200 ng/mL a 20 anni) e diminuiscono costantemente con l'et, scendendo a circa 80 ng/mL a 60 anni

While surveying the literature in preparation of this manuscript we have also noticed and reported an increasing interest in the role that GSTs play in neurodegeneration, where isozymes belonging to the family may be either up-regulated, mutated or absent, according to the different diseases

Genes Nutr (2011) 6:26174

Furthermore, the Sod1 G86R mouse models were developed, which express the missense mutation Gly86 to Arg of the murine SOD1 enzyme (Ripps et al., 1995), reported in the corresponding amino acid residue (position 85) of some fALS patients (Rosen et al., 1993)