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A total of 80% of AST activity is located in the mitochondria (mAST), with 20% in the cytosol (cAST) of hepatocytes, and extrahepatic activity is high in the skeletal muscle, heart, kidneys, brain, and pancreas [24]

J Neurosci 23:75867591 Kopec K, Flood DG, Gasior M, McKenna BAW, Zuvich E, Schreiber J, Salvino JM, Durkin JT, Ator MA, Marino MJ (2010) Glycine transporter (GlyT1) inhibitors with reduced residence time increase prepulse inhibition without inducing hyperlocomotion in DBA/2 mice

J Hepatol 73(2):423440

Results are expressed as the percentage inhibition of 4,5-diaminofluorescein oxidation relative to the concentration of the NO scavenging compound