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In most popular and general assays for GGT, -glutamyl derivatives of 4-nitroaniline are often used as the donor to allow for spectrophotometric measurements of enzyme activity [84]

The GD group exhibited higher levels of serum and muscle antioxidant enzymes along with upregulated expression of Nrf2 and its downstream targets (HO-1, NQO1) 24

In this regard, our in vitro experiments evidenced that under GSH depletion the increased NO availability induced S-nitrosylation of nuclear resident p53 at different cysteine residues, among which the Cys124 was essential for the induction of p53-mediated antioxidant response in C2C12 myoblasts

This approach has been especially useful for studying endometrial receptivity, where spatial organization is critical for function