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Despite this failure, a number of exploratory endpoints included in phase 2/3 trials suggest AMX0035 and TUDCA has the potential to significantly slow clinical worsening, improve quality of life, and prolong survival in ALS

pylori by allowing it to evade sites where host defenses are most reactive (Mahdavi et al., 2002)

The only adverse effect noted was diarrhea resulting from very high intakes of 10 to 20 g/day of calcium D-pantothenate (43)
