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Nonetheless, several authors reported that this proteolytic activity could be only marginally connected to the pharmacological effects

[30] Interestingly, and of particular importance for the potential of NSI-189 as a cognitive enhancer in healthy individuals, the drug was found to enhance long-term potentiation, a form of synaptic plasticity which underlies learning, in the hippocampus of wild-type (control) animals

MOTS-C supports metabolic health by targeting the skeletal muscle and enhancing glucose metabolism

In addition, recent studies have identified betaine as a potential exercise mimetic capable of alleviating cellular senescence and exerting broad longevity-promoting effects across multiple organ systems [36, 66]