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For hair, PDRN is most useful in patients whose hair loss has an inflammatory or post-inflammatory component: telogen effluvium after stress, hair loss following autoimmune flares, recovery after hair transplant procedures, or scalp inflammation accompanying conditions like seborrheic dermatitis

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This tolerance partly explains the alertness of chronic alcohol users at blood alcohol levels that, in others, would cause coma or death [238,239,240,241]
