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Cytokine Influence on GSH Production In the macrophages of individuals with HIV, the gene expression for the formation of the enzymes of GSH synthesis GCLC, GCLM, GSS, and GGT1 appear to be down-regulated [53]

Antioxidant Defense: It neutralizes free radicals, preventing oxidative stress and cellular damage

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A retrospective analysis of 731 incident cases of pulmonary arterial hypertension showed that GGT, AST to ALT ratio, and neutrophil to lymphocyte ratio (NLR) were reliable prognostic biomarkers at baseline and follow-up, with predictive power comparable to the gold standard for risk stratification of patients with pulmonary arterial hypertension [78]