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SIRT1 activation promotes numerous anti-aging effects including enhanced mitochondrial biogenesis, improved stress resistance, reduced inflammation, and activation of cellular quality control mechanisms that remove damaged proteins and organelles

By inhibiting NNMT, helps preserve nicotinamide for conversion to NAD+supporting cellular repair, DNA maintenance, and healthy aging processes

doi: 10.1016/s0959-440x(02)00391-3

A high-fat/high-protein, atkins-type diet exacerbates (in Eng)
