glutathione conjugates reaction A: conjugation to a generic xenobiotic (X) via GST results 16 Phase II reactions Conjugation

As a result, their data showed a GSSG level five times higher in the fluorometric method relative to enzymatic method

Moreover, many intermediary metabolites generated from glycolytic and oxidative phosphorylation serve as cofactors or substrates of epigenetic enzymes involved in post-translational modification and gene expression

Methionine can also be converted to cytosine, the precursor of gluthione, which is essential in detoxification of the liver

The stability of the A assemblies could arise from either the formation of a strong ionic complex or the formation of covalent cross-links, which may include transglutaminase (TGase)-induced cross-linking between the glutamyl side chains and the -amino groups of lysine