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Correspondingly, disturbance in the gut microbiota can lead to functional impairments in the digestive system, resulting in spleen deficiency syndrome [84]

Pharmgenomics Pers Med 7, 203215

DPP-4i plays an anti-apoptotic role by regulating the mitogen-activated protein kinase (MAPK)/ERK, phosphatidylinositol-3-kinase (PI3K)/AKT and NF-B signaling pathways
CYP1A is considered as one of the major CYP isoenzymes in liver tissue that may provoke metabolic activation of BaP and production reactive metabolites which subsequently lead to lipid peroxidation, oxidative damage, and apoptosis (Aboutabl et al