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Costa F, Giorgini G, Minnelli C, et al

These genes regulate crucial cellular processes such as tumor suppression, chromatin remodeling, and cell signaling, which, when disrupted, accelerate tumorigenesis

In addition to NCOA4, autophagy receptor SQSTM1/p62 mediates iron exporter FPN1 (ferroportin1) degradation in lysosome, subsequently accumulates cellular iron levels, and facilitates ferroptosis [69]

10.1007/s13346-018-0510-z 27 CostaI
