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While minor non-EV proteins may still be present, subsequent analyses focused on proteins consistently enriched in EV fractions across all samples to minimize potential confounding effects on proteomic profiling

In addition to these environmental factors, other population differences, such as linkage disequilibrium of the GPx-1 locus with other specific modifying genes, the influence of other gene variants that act to modulate GPx-1 activity [such as the SelP subtypes mentioned above (252)], and/or the presence of other gene variants that act in concert with GPx-1 to modify disease risk may also explain differences among studies performed in different populations

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(2015) found that in skin keratinocytes at a concentration of 10 mM vitamin E, the enzyme activity of GST significantly decreased by 74% ( p 0.001)