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Other botanical remedies which have antioxidant and anti-inflammatory activity, such as turmeric, have a long history of use in skin disorders such as acne [29]

Giudice PL, Bonomini M, Arduini A Cardiovascular drugs and therapy 2016

The choice depends on timeline, medical history, and priorities

Melatonin adjusts the expression pattern of clock genes in the suprachiasmatic nucleus and induces antidepressant-like effect in a mouse model of seasonal affective disorder
