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glutathione synthetase function Biosynthesis of - a two step reaction catalyzed by two ATP Glutathione Synthetase - an overview
Description
Glioblastoma (GBM) is the most common primary intracranial malignant tumor
Glutathione was first observed in 1888 by Rey-Pailhade
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Aberrant N6-methyladenosine (m6A) modification of GPX4 mRNA contributes significantly to epigenetic tumorigenesis, and here, we report that selective methyltransferase-like 3 (METTL3)-dependent m6A methylation of GPX4 plays a key role in C5AR1 knockdown-induced ferroptosis induction
