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References Institute of Medicine (US) Standing Committee on the Scientific Evaluation of Dietary Reference Intakes
A reasonable titration schedule might look like this: Week 1: 200mcg once daily Week 2: 300mcg once daily Week 3 onward: 300-500mcg based on response and tolerance Optimizing injection technique Poor injection technique contributes to injection site reactions and potentially to other effects like nausea from anxiety around the process
10.1016/s1097-2765(00)00028-9 13 EdwardsC.CanfieldJ.CopesN.BritoA.RehanM.LippsD.et al (2015)
Mood Evidence has linked depression with B-12 deficiency
