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Description
Research shows the peptide stimulates expression of brain-derived neurotrophic factor (BDNF) and cyclic-AMP responsive element binding protein 1 (CREB1) by regulating melatonin synthesis and circadian gene expression

Primary Handling Editors: Ross Bathgate, Aylin Bircan, and Rupali Sathe
Astrocytic reactivity reflects activation of complex molecularly defined programmes which define remodelling of biochemical, morphological, metabolic, and physiological properties of astroglia leading to an upregulation or loss of homoeostatic cascades, or in gain of new protective or regenerative functions
Material and Methods Murine model of psoriasis-like skin inflammation In vivo experiments involved 6-week-old C57BL/6 J female mice (Japan SLC, Shizuoka, Japan)
