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4.4 Inducible HSP70 (HSP70i) DNA Indeed, HSP70i is the core participant in vitiligo predominantly through HSP70i-plasmacytoid dendritic cells (pDCs)-IFN--CXCL9 and CXCL10-cytotoxic T lymphocyte (CTL) axis

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However, secukinumab treatment in patients with active nonsegmental vitiligo (NSV) contributed to disease progression in 7/8 patients with no general reduction in CXCL9/10, sCD25/27, Th1 cells, or cytotoxic cells, resulting in early termination of study (89)

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