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Patients with active malignancies, pregnancy, or significant hormonal imbalances should not use investigational peptides without specialist clearance

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By blocking this enzyme, scientists can investigate its roles in NAD+ regulation, mitochondrial function, and metabolic health in experimental settings

More recent research has explored AOD9604 for other potential applications beyond obesity, including osteoarthritis treatment based on observations of cartilage regeneration properties in preclinical models, though clinical validation of these additional indications is limited