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Diagnosis and management of genetic iron overload disorders
In addition, in vivo and in vitro experimental showed that tumor necrosis factor- (TNF-)-mediated BBB breakdown is linked to COXs up-regulation the expression and activity of matrix metalloproteinases (MMPs) (Mark et al., 2001
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To this end, elevated Hcy levels inhibit the enzymatic activity of mitochondrial complex IIII that is associated with higher cytochrome c release in rat ischemic brain as a model of cerebral infarction-related disease
