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One proposed mechanism is that SNAC temporarily associates with drug molecules, increasing their lipophilicity and making it easier for them to cross biological membranes

NNMT depletes the NAD+ precursor pool by methylating nicotinamide the same nicotinamide that the salvage pathway would otherwise convert back into NAD+ via the enzyme NAMPT

LRRK2, also known as dardarin, is a kinase with guanosine triphosphatase (GTPase) and scaffolding domains [48]
