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Their inclusion in treatment plans may help maintain long-term immunological health, decrease side effects, and lessen reliance on synthetic immunosuppressants (57)

13,99 This process leads to an increased number of memory CD4 and CD8 T lymphocytes with age, and a decrease of TCR diversity in naive T cells, which suppresses the responsiveness of T cells to neoantigens (Fig

Moreover, Propionibacterium acnes infection of the prostate organ may have a major impact on the infiltration of CD4 + , IL-17 + , and Treg cells into prostate tissue in patients with benign prostatic hyperplasia (BPH)

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