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Finally, a four-year, multicenter, clinical trial in 421 diabetic patients with distal symmetric sensorimotor polyneuropathy found no difference between oral administration of 600 mg/day of lipoic and placebo on the primary endpoint, a composite score that assessed neuropathic impairment of the lower limbs and nerve conduction (78)

Ul Hasan, Annals of Microbiology 60, (2010) 7580

Injecting the solvent slowly down the vial wall not directly onto the lyophilized cake
