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Inclusion criteria for the IMPRESS trial included stable disease, dorsal curvature between 30 and 90 degrees, and intact erectile function with or without use of phosphodiesterase 5 inhibitors
For instance, SEIP-1, a homolog of human SEIPIN (a nonenzymatic protein encoded by the Berardinelli-Seip congenital lipodystrophy type 2 gene) [39] can localize to ER-LD contact sites and act as membrane anchors to enable the lipid transfer and LD growth in nematodes [40,41]
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