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As Eric Verdin documented in a 2015 review, NAD+ is involved in energy production, DNA repair, and activating proteins called sirtuins (which help regulate how cells age) in virtually every cell in the body

(1982) Antioxidants, metabolic rate and ageing in Drosophila

Genetic and environmental interplay : mutations in SNCA , LRRK2 , PINK1 , and VPS35 interact with toxins and metabolic stressors to trigger degeneration

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