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This peroxide induces apoptosis in neuronal cells which are particularly sensitive to its toxic effects [51]

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All of these culprits combined with genetic susceptibility can trigger exaggerated immune reactions to the many everyday things were exposed to

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More recently, mGPDHs protective function was validated in vivo: in a mouse model of sepsis-induced acute lung injury, mGPDH knockdown exacerbated lung injury, vascular leakage, inflammation and oxidative damage, accompanied by elevated ferroptotic markers 100

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[DOI] [PubMed] [Google Scholar] 68.Ezeria D, Takano Y, Hanaoka K, Urano Y, Dick TP

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