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Description
Decreased histone deacetylase activity in chronic obstructive pulmonary disease

Presently, the drugs available for treatment, including crizotinib or erlotinib, are tyrosine kinase inhibitors (TKIs) for cancer treatment (primarily lung adenocarcinoma), exhibiting EGFR mutations or EML4-ALK fusions

Mild headache may occur during the first few days of use or after increasing the dose

2020;146:e20200771
