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23 The importance of autophagy extends to cardiac development, as evidenced by embryonic lethality and myocardial developmental defects in Atg13-knockout mice, underscoring the indispensable roles of Atg13 and FIP200 in both autophagy and heart formation (Fig

Head-to-head data from SURPASS-2 showed tirzepatide 15 mg reducing A1c by approximately 2.5% compared to semaglutide 1 mg at approximately 1.9%