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1 H MRS studies in ME/CFS and long COVID are however still rare, in fact we are aware of only one, showing decreased creatine concentration in long COVID, which correlated inversely with muscle pain [20]
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Mice undergoing in vivo reprogramming were found to become depleted in B 12 and show signs of methionine starvation while supplementing reprogramming mice and cells with B 12 increased reprogramming efficiency, indicating a cell-intrinsic effect
