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Additionally, it negatively affects the activity of energy metabolism-related neurons in the hypothalamic arcuate nucleus (e.g., increases appetite and energy intake by elevating spiny mouse state-related protein: agouti related protein (AgRP) neurons and decreasing levels of allantoinogen proopiomelanocortin (POMC) neurons)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Samimi M, Jamilian M, Ebrahimi FA, Rahimi M, Tajbakhsh B, Asemi Z
Liraglutide was approved for use in the United States in January 2010
